Platelet-Rich Plasma Pre-Procedure Instructions

Before Arriving for Your Exam

  • STOP ALL ANTI-INFLAMMATORIES AT LEAST 10 DAYS PRIOR TO PROCEDURE
  • Pick up pre-procedure medications (valium and/or pain medication)
  • You should not have PRP therapy if you have:
    • Abnormal platelet function
    • Active systemic infection
    • Active cancer
    • Low-platelet count
    • Severe anemia

After Arriving

An hour before your scheduled PRP therapy, blood is collected and the platelets, which contain your body’s natural healing components (growth factors), are concentrated in a centrifuge. The blood is collected via venipuncture.

During Your Exam

During the treatment, a local anesthetic is used on the affected region including superficial soft tissues. Lidocaine cannot be injected into the diseased tissue as it may deactivate the platelets. After superficial tissues are injected, platelet rich plasma is injected into the target tissue (joint/tendon/ligament) under ultrasound-guidance to stimulate and enhance healing.

In most cases, one treatment is enough, but in certain cases between one and three treatments are recommended for maximum benefit over four to six weeks.

After Your Exam

Immediately after the procedure, you will remain lying down and under observation for a few minutes up to 30 minutes.

 

PRP Site Care

  • Keep the PRP site clean and dry.
  • Leave the bandage on for 12 to 24 hours and then replace the bandage with a Band-Aid until the site heals.
  • You may shower but change the bandage if it gets wet.
  • DO NOT use ice on the PRP site because ice reduces swelling. The therapy is meant to cause swelling, which helps you heal.
  • You may have some swelling and bruising for three to seven days.

Pain and Drugs

  • You may have severe pain at the PRP site for 24 to 48 hours. Please use Tylenol or Ultram (tramadol) as needed, but do not take more than 3,000 mg of Tylenol in 24 hours.
  • You may be given narcotic pain drugs. NOTE: Some narcotic pain drugs have Tylenol in them. Count such drugs in the 24-hour 3,000 mg Tylenol limit.
  • Narcotics cause constipation. If taking a narcotic, please use a stool softener such as Colace. Please also drink more water and eat more fiber. DO NOT go more than two or three days without a bowel movement. Use a laxative or enema when needed.
  • DO NOT use any drugs that have the following in them for two weeks:
    • Aspirin
    • Ibuprofen
    • Naproxen
    • Other anti-inflammatory (anti-swelling) drugs (Motrin, Advil, Aleve, Voltaren, Celebrex, Mobic, Daypro, Feldene, Lodine, Orudis or Ansaid)

Activity

You will be told which activities you may and may not do, but in most cases:

  • For PRP in the arm, wrist or shoulder, do not pull, tug, grasp, lift weight or grip with the arm, wrist or shoulder for six weeks. Also, do not do any motion again and again.
  • For PRP in the hip, knee, ankle or foot, use crutches for a day or more until you can walk without the pain getting worse.

Driving

  • DO NOT drive for 24 hours after having anesthesia or taking narcotic pain drugs.
  • If you have PRP in your hip, knee, ankle or foot, please have someone drive you home.
  • You may drive home if you had PRP in your wrist, arm or shoulder without a nerve block and drive an automatic transmission car.

 

PRP therapy takes time to work. It is not like a steroid shot that will make you feel better right away. You may feel more pain at first, since we are causing swelling in the area that was already sore. The swelling is needed for the blood cells to start helping you heal for the long term. Please be patient.